Adipose-derived stromal cells for nonhealing wounds: Emerging opportunities and challenges.

ABSTRACT: Wound healing complications affect thousands of people each year, thus constituting a profound economic and medical burden. Chronic wounds are a highly complex problem that usually affects elderly patients as well as patients with comorbidities such as diabetes, cancer (surgery, radiotherapy/chemotherapy) or autoimmune diseases. Currently available methods of their treatment are not fully effective, so new solutions are constantly being sought. Cell-based therapies seem to have great potential for use in stimulating wound healing. In recent years, much effort has been focused on characterizing of adipose-derived mesenchymal stromal cells (AD-MSCs) and evaluating their clinical use in regenerative medicine and other medical fields. These cells are easily obtained in large amounts from adipo

SUBMITTER: Deptula M 

PROVIDER: S-EPMC8247932 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature