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Lockdown effects on Parkinson's disease during COVID-19 pandemic: a pilot study.

ABSTRACT: The coronavirus-disease 2019 (COVID-19) outbreak precipitated prolonged lock-down measures. The subsequent social distancing, isolation, and reduction in mobility increased psychological stress, which may worsen Parkinson's disease (PD). Therefore, telemedicine has been proposed to provide care to PD patients. To evaluate the effects of lock-down on motor and nonmotor symptoms in PD patients during the COVID-19 pandemic and the feasibility of telemedicine. Motor and nonmotor aspects were longitudinally assessed using structured questionnaires at baseline (in-person, February 2020) and at follow-up (remote web-based video, lock-down) evaluation. Of the seventeen PD patients evaluated at baseline, fourteen agreed to participate in, and completed follow-up evaluations. There was an impairment of nonmotor aspects measured with the MDS-UPDRS part I (p < 0.001) during lock-down. Nine patients participated independently in the telemedicine evaluation while five needed help from relatives. Our preliminary findings suggest an impairment of nonmotor symptoms in PD patients and support the feasibility and need for telemedicine in monitoring PD patients during the COVID-19 pandemic, to guarantee optimal assistance with reducing the burden of infection. Our findings also suggest that movement disorder clinics should be carefully considering socio-demographics and clinical features when developing telemedicine programs.

SUBMITTER: Falla M

PROVIDER: S-EPMC8248756 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Parkinson's Disease Remote Patient Monitoring During the COVID-19 Lockdown.

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Delayed Colorectal Cancer Care During Coronavirus Disease (COVID-19) Pandemic (DECOR-19)

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Lockdown Effects on Healthy Cognitive Aging During the COVID-19 Pandemic: A Longitudinal Study.

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Altered alcohol consumption during COVID-19 pandemic lockdown.

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Effects of the COVID-19 Pandemic on Parkinson's Disease: a Single-Centered Qualitative Study.

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Project description:The COVID-19 pandemic [1] resulted in many countries imposing a lockdown, which in turn reduces sunlight exposure and alters daily social schedules. Since these are the main entrainment factors for biological rhythms [2], we hypothesized that the lockdown may have affected sleep and circadian rhythms. We indeed show that participants slept longer and later during lockdown weekdays, and exhibited lower levels of social jetlag. While this may seem to be an overall improvement of sleep conditions, chronotype was also delayed under the lockdown. This signature of a weaker light-dark cycle should be monitored attentively since it may progressively cause disruptive effects on sleep and circadian rhythms, affecting human performance and health [3].

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Project description: Not available

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Project description: Not available

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Optimal Lockdown Policy for Vaccination during COVID-19 Pandemic.

Project description:As the COVID-19 spreads across the world, many nations impose lockdown measures at the early stage of the pandemic to prevent the spread of the disease. Controversy surrounds the lockdown as it is a choice between economic freedom and public health. The ultimate solution to a pandemic is to vaccinate a massive population to achieve herd immunity. However, the whole vaccination programme is a long and complicated process. The virus and the vaccine will persist for quite a long time. How to gradually ease the lockdown based on vaccination progress is an important issue, as both economic and epidemiological issues are involved. In this paper, we extend the classic SIR model to find optimal decision making to balance between economy and public health in the process of vaccination rollout. The model provides an approach of vaccine value estimation. Our results provide scientific suggestion for policymakers to make important decisions about when to start the lockdown and how strong it should be over the entire vaccination cycle.

| S-EPMC8119293 | biostudies-literature

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Project description:How can we explain the rise in diffuse political support during the Covid-19 pandemic? Recent research has argued that the lockdown measures generated political support. In contrast, I argue that the intensity of the pandemic rallied people around political institutions. Collective angst in the face of exponentially rising Covid-19 cases depresses the usual cognitive evaluations of institutions and leads citizens to rally around existing intuitions as a lifebuoy. Using a representative Dutch household survey conducted over March 2020, I compare the lockdown effect to the dynamic of the pandemic. I find that the lockdown effect is driven by pre-existing time trends. Accounting for non-linearities in time makes the lockdown effect disappear. In contrast, more flexible modelling techniques reveal a robust effect of Covid-19 infections on political trust. In line with an anxiety effect, I find that standard determinants of political trust - such as economic evaluations and social trust - lose explanatory power as the pandemic spreads. This speaks to an emotionally driven rally effect that pushes cognitive evaluations to the background.

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