Ontology highlight
ABSTRACT:
SUBMITTER: Matteucci S
PROVIDER: S-EPMC8251831 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Matteucci Sara S Camponeschi Francesca F Clémancey Martin M Ciofi-Baffoni Simone S Blondin Geneviève G Banci Lucia L
Angewandte Chemie (International ed. in English) 20210524 27
Human anamorsin is an iron-sulfur (Fe-S)-cluster-binding protein acting as an electron donor in the early steps of cytosolic iron-sulfur protein biogenesis. Human anamorsin belongs to the eukaryotic CIAPIN1 protein family and contains two highly conserved cysteine-rich motifs, each binding an Fe-S cluster. In vitro works by various groups have provided rather controversial results for the type of Fe-S clusters bound to the CIAPIN1 proteins. In order to unravel the knot on this topic, we used an ...[more]