Ultrasensitive On-Field Luminescence Detection Using a Low-Cost Silicon Photomultiplier Device.

ABSTRACT: The availability of portable analytical devices for on-site monitoring and rapid detection of analytes of forensic, environmental, and clinical interest is vital. We report the development of a portable device for the detection of biochemiluminescence relying on silicon photomultiplier (SiPM) technology, called LuminoSiPM, which includes a 3D printed sample holder that can be adapted for both liquid samples and paper-based biosensing. We performed a comparison of analytical performance in terms of detectability with a benchtop luminometer, a portable cooled charge-coupled device (CCD sensor), and smartphone-integrated complementary metal oxide semiconductor (CMOS) sensors. As model systems, we used two luciferase/luciferin systems emitting at different wavelengths using purified protein so

SUBMITTER: Calabretta MM 

PROVIDER: S-EPMC8253476 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature