Exploring valence bias as a metric for frontoamygdalar connectivity and depressive symptoms in childhood.

ABSTRACT: Negativity bias is a core feature of depression that is associated with dysfunctional frontoamygdalar connectivity; this pathway is associated with emotion regulation and sensitive to neurobiological change during puberty. We used a valence bias task (ratings of emotional ambiguity) as a potential early indicator of depression risk and differences in frontoamygdalar connectivity. Previous work using this task demonstrated that children normatively have a negative bias that attenuates with maturation. Here, we test the hypothesis that persistence of this negativity bias as maturation ensues may reveal differences in emotion regulation development, and may be associated with increased risk for depression. In children aged 6-13 years, we tested the moderating role of puberty on relationships

SUBMITTER: Petro NM 

PROVIDER: S-EPMC8255333 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature