H₂ FPEF score predicts atherosclerosis presence in patients with systemic connective tissue disease.

ABSTRACT:

Background

Cardiovascular diseases are common cause of morbidity and mortality in patients with systemic connective tissue diseases (SCTD) due to accelerated atherosclerosis which couldn't be explained by traditional risk factors (CVDRF).

Hypothesis

We hypothesized that recently developed score predicting probability of heart failure with preserved ejection fraction (H₂ FPEF), as well as a measure of right ventricular-pulmonary vasculature coupling [tricuspid annular plane systolic excursion (TAPSE)/pulmonary artery systolic pressure (PASP) ratio], are predictive of atherosclerosis in SCTD.

Methods

203 patients (178 females) diagnosed with SCTD underwent standard and stress-echocardiography (SE) with TAPSE/PASP and left ventricular (LV) diastolic filling pr

SUBMITTER: Vasilev V 

PROVIDER: S-EPMC8259163 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature