Management impact of ¹⁸F-DCFPyL PET/CT in hormone-sensitive prostate cancer patients with biochemical recurrence after definitive treatment: a multicenter retrospective study.

ABSTRACT:

Purpose

The aim of this study was to investigate whether an early, accurate identification of disease using ¹⁸F-DCFPyL PET/CT imaging resulted in a change of decision on treatment management, for individual patients with biochemically recurrent (BCR), hormone-sensitive prostate cancer.

Methods

In this retrospective study, a total of 253 patients with BCR who underwent restaging ¹⁸F-DCFPyL PET/CT were assessed. Two urologists specialized in uro-oncology were asked to formulate a preferred treatment for each patient before and after knowing the results of the ¹⁸F-DCFPyL PET/CT.

Results

Out of 253 patients, 191 (75%) underwent robot-assisted radical prostatectomy (RARP) as primary therapy, and 62 (25%) external beam radiation therapy (EBR

SUBMITTER: Meijer D 

PROVIDER: S-EPMC8263452 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature