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Differences in Clinical Features among Different Onset Patterns in Moyamoya Disease.


ABSTRACT: Moyamoya disease is characterized by severe stenosis at the ends of the bilateral internal carotid arteries and the development of collateral circulation. The disease is very diverse in terms of age at onset, onset patterns, radiological findings, and genetic phenotypes. The pattern of onset is mainly divided into ischemic and hemorrhagic onsets. Recently, the opportunity to identify asymptomatic moyamoya disease, which sometimes manifests as nonspecific symptoms such as headache and dizziness, through screening with magnetic resonance imaging has been increasing. Various recent reports have investigated the associations between the clinical features of different onset patterns of moyamoya disease and the corresponding imaging characteristics. In this article, we have reviewed the natural history, clinical features, and imaging features of each onset pattern of moyamoya disease.

SUBMITTER: Hirano Y 

PROVIDER: S-EPMC8267932 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature

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Differences in Clinical Features among Different Onset Patterns in Moyamoya Disease.

Hirano Yudai Y   Miyawaki Satoru S   Imai Hideaki H   Hongo Hiroki H   Teranishi Yu Y   Dofuku Shogo S   Ishigami Daiichiro D   Ohara Kenta K   Koizumi Satoshi S   Ono Hideaki H   Nakatomi Hirofumi H   Saito Nobuhito N  

Journal of clinical medicine 20210625 13


Moyamoya disease is characterized by severe stenosis at the ends of the bilateral internal carotid arteries and the development of collateral circulation. The disease is very diverse in terms of age at onset, onset patterns, radiological findings, and genetic phenotypes. The pattern of onset is mainly divided into ischemic and hemorrhagic onsets. Recently, the opportunity to identify asymptomatic moyamoya disease, which sometimes manifests as nonspecific symptoms such as headache and dizziness,  ...[more]

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