The Implications of Pruritogens in the Pathogenesis of Atopic Dermatitis.
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ABSTRACT:
SUBMITTER: Wong LS
PROVIDER: S-EPMC8269281 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
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The Implications of Pruritogens in the Pathogenesis of Atopic Dermatitis.
Wong Lai-San LS Yen Yu-Ta YT Lee Chih-Hung CH
International journal of molecular sciences 20210705 13
Atopic dermatitis (AD) is a prototypic inflammatory disease that presents with intense itching. The pathophysiology of AD is multifactorial, involving environmental factors, genetic susceptibility, skin barrier function, and immune responses. A recent understanding of pruritus transmission provides more information about the role of pruritogens in the pathogenesis of AD. There is evidence that pruritogens are not only responsible for eliciting pruritus, but also interact with immune cells and ac ...[more]
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