Costs of Illness of Spinal Muscular Atrophy: A Systematic Review.

ABSTRACT:

Objectives

The objective of our study was to conduct a systematic literature review of estimates of costs of illness of spinal muscular atrophy (SMA).

Methods

We searched MEDLINE (through PubMed), CINAHL, Embase, Web of Science, National Health Service Economic Evaluation Database, and the National Health Service Health Technology Assessment Database for studies published from inception up until 31 August, 2020, reporting direct medical, direct non-medical, and/or indirect costs of any phenotype of SMA. Two reviewers independently screened records for eligibility, extracted the data, and assessed studies for risk of bias using the Newcastle-Ottawa Scale. Costs were adjusted and converted to 2018 US dollars.

Results

The search identified 14 studies from eight countries

SUBMITTER: Landfeldt E 

PROVIDER: S-EPMC8270802 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature