Annular Fiber Probe for Interstitial Illumination in Photoacoustic Guidance of Radiofrequency Ablation.

ABSTRACT: Unresectable liver tumors are commonly treated with percutaneous radiofrequency ablation (RFA). However, this technique is associated with high recurrence rates due to incomplete tumor ablation. Accurate image guidance of the RFA procedure contributes to successful ablation, but currently used imaging modalities have shortcomings in device guidance and treatment monitoring. We explore the potential of using photoacoustic (PA) imaging combined with conventional ultrasound (US) imaging for real-time RFA guidance. To overcome the low penetration depth of light in tissue, we have developed an annular fiber probe (AFP), which can be inserted into tissue enabling interstitial illumination of tissue. The AFP is a cannula with 72 optical fibers that allows an RFA device to slide through its lumen,

SUBMITTER: Kruit H 

PROVIDER: S-EPMC8271966 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature