Initial action output and feedback-guided motor behaviors in autism spectrum disorder.

ABSTRACT:

Background

Sensorimotor issues are common in autism spectrum disorder (ASD), related to core symptoms, and predictive of worse functional outcomes. Deficits in rapid behaviors supported primarily by feedforward mechanisms, and continuous, feedback-guided motor behaviors each have been reported, but the degrees to which they are distinct or co-segregate within individuals and across development are not well understood.

Methods

We characterized behaviors that varied in their involvement of feedforward control relative to feedback control across skeletomotor (precision grip force) and oculomotor (saccades) control systems in 109 individuals with ASD and 101 age-matched typically developing controls (range: 5-29 years) including 58 individuals with ASD and 57 controls who comple

SUBMITTER: Unruh KE 

PROVIDER: S-EPMC8272343 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature