Epidemiological and genomic characteristics of Acinetobacter baumannii from different infection sites using comparative genomics.

ABSTRACT:

Background

Acinetobacter baumannii is a common nosocomial pathogen that poses a huge threat to global health. Owing to the severity of A. baumannii infections, it became necessary to investigate the epidemiological characteristics of A. baumannii in Chinese hospitals and find the reasons for the high antibiotic resistance rate and mortality. This study aimed to investigate the epidemiologic and genetic characteristics of A. baumannii isolated from patients with hospital acquired pneumonia (HAP), bloodstream infection (BSI) and urinary tract infection (UTI) in China and uncover potential mechanisms for multi-drug resistance and virulence characteristics of A. baumannii isolates.

Results

All isolates were classified into two primary clades in core gene-based phylogenetic relat

SUBMITTER: Bian X 

PROVIDER: S-EPMC8272988 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature