Alteration of corneal biomechanical properties in patients with dry eye disease.

ABSTRACT:

Purpose

To evaluate the association between symptoms and signs of dry eye diseases (DED) with corneal biomechanical parameters.

Methods

This cross-sectional study enrolled 81 participants without history of ocular hypertension, glaucoma, keratoconus, corneal edema, contact lens use, diabetes, and ocular surgery. All participants were evaluated for symptoms and signs of DED using OSDI questionnaire, tear film break-up time (TBUT), conjunctival and corneal staining (NEI grading) and Schirmer test. Corneal biomechanical parameters were obtained using Corvis ST. Mixed-effects linear regression analysis was used to determine the association between symptoms and signs of DED with corneal biomechanical parameters. Difference in corneal biomechanical parameter between participants w

SUBMITTER: Satitpitakul V 

PROVIDER: S-EPMC8274861 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature