Ontology highlight
ABSTRACT:
SUBMITTER: Petrick L
PROVIDER: S-EPMC8275155 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Petrick Lauren L Imani Partow P Perttula Kelsi K Yano Yukiko Y Whitehead Todd T Metayer Catherine C Schiffman Courtney C Dolios Georgia G Dudoit Sandrine S Rappaport Stephen S
Leukemia research 20210424
The etiology of pediatric acute myeloid leukemia (AML) is largely unknown, but evidence for mutations in utero and long latency periods suggests that environmental factors play a role. Therefore, we used untargeted metabolomics of archived newborn dried blood spots (DBS) to investigate neonatal exposures as potential causal risk factors for AML. Untargeted metabolomics profiling was performed on DBS punches from 48 pediatric patients with AML and 46 healthy controls as part of the California Chi ...[more]