Topological Data Analysis of C. elegans Locomotion and Behavior.
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ABSTRACT:
SUBMITTER: Thomas A
PROVIDER: S-EPMC8276312 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Publications
Topological Data Analysis of <i>C. elegans</i> Locomotion and Behavior.
Thomas Ashleigh A Bates Kathleen K Elchesen Alex A Hartsock Iryna I Lu Hang H Bubenik Peter P
Frontiers in artificial intelligence 20210629
We apply topological data analysis to the behavior of <i>C. elegans</i>, a widely studied model organism in biology. In particular, we use topology to produce a quantitative summary of complex behavior which may be applied to high-throughput data. Our methods allow us to distinguish and classify videos from various environmental conditions and we analyze the trade-off between accuracy and interpretability. Furthermore, we present a novel technique for visualizing the outputs of our analysis in t ...[more]
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