Cardiovascular and renal burdens of metabolic associated fatty liver disease from serial US national surveys, 1999-2016.

ABSTRACT:

Background

Non-communicable chronic diseases have become the leading causes of disease burden worldwide. The trends and burden of "metabolic associated fatty liver disease" (MAFLD) are unknown. We aimed to investigate the cardiovascular and renal burdens in adults with MAFLD and non-alcoholic fatty liver disease (NAFLD).

Methods

Nationally representative data were analyzed including data from 19,617 non-pregnant adults aged ≥20 years from the cross-sectional US National Health and Nutrition Examination Survey periods, 1999 to 2002, 2003 to 2006, 2007 to 2010, and 2011 to 2016. MAFLD was defined by the presence of hepatic steatosis plus general overweight/obesity, type 2 diabetes mellitus, or evidence of metabolic dysregulation.

Results

The prevalence of MAFLD increase

SUBMITTER: Zhang HJ 

PROVIDER: S-EPMC8280082 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature