Dataset Information

The incidence and outcome of postoperative hepatic encephalopathy in patients with cirrhosis.

ABSTRACT:

Background

Cirrhosis is associated with increased perioperative risks related to hepatic decompensation. However, data are lacking regarding the incidence and outcomes of postoperative hepatic encephalopathy (HE).

Objective

To determine the incidence of HE postoperatively, factors associated with its development, and its association with in-hospital mortality.

Methods

Retrospective cohort study of 583 patients with cirrhosis undergoing non-hepatic surgery over a 10-year period. Outcomes included postoperative HE and in-hospital mortality and were, respectively, evaluated using multi-state modeling and Fine-Gray competing risk regression (with postoperative HE as a time-varying covariate).