Ontology highlight
ABSTRACT:
SUBMITTER: Esmaeili V
PROVIDER: S-EPMC8285666 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Esmaeili Vahid V Tamura Keita K Muscinelli Samuel P SP Modirshanechi Alireza A Boscaglia Marta M Lee Ashley B AB Oryshchuk Anastasiia A Foustoukos Georgios G Liu Yanqi Y Crochet Sylvain S Gerstner Wulfram W Petersen Carl C H CCH
Neuron 20210601 13
The neuronal mechanisms generating a delayed motor response initiated by a sensory cue remain elusive. Here, we tracked the precise sequence of cortical activity in mice transforming a brief whisker stimulus into delayed licking using wide-field calcium imaging, multiregion high-density electrophysiology, and time-resolved optogenetic manipulation. Rapid activity evoked by whisker deflection acquired two prominent features for task performance: (1) an enhanced excitation of secondary whisker mot ...[more]