Unknown

Dataset Information

0

A functional mixed model for scalar on function regression with application to a functional MRI study.


ABSTRACT: Motivated by a functional magnetic resonance imaging (fMRI) study, we propose a new functional mixed model for scalar on function regression. The model extends the standard scalar on function regression for repeated outcomes by incorporating subject-specific random functional effects. Using functional principal component analysis, the new model can be reformulated as a mixed effects model and thus easily fit. A test is also proposed to assess the existence of the subject-specific random functional effects. We evaluate the performance of the model and test via a simulation study, as well as on data from the motivating fMRI study of thermal pain. The data application indicates significant subject-specific effects of the human brain hemodynamics related to pain and provides insights on how the effects might differ across subjects.

SUBMITTER: Ma W 

PROVIDER: S-EPMC8286587 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC10655915 | biostudies-literature
| S-EPMC3074471 | biostudies-literature
| S-EPMC4943585 | biostudies-literature
| S-EPMC10065478 | biostudies-literature
| S-EPMC3270884 | biostudies-literature
| S-EPMC3677735 | biostudies-literature
| S-EPMC6191855 | biostudies-literature
| S-EPMC4620087 | biostudies-literature
| S-EPMC7517594 | biostudies-literature
| S-EPMC6684443 | biostudies-literature