Prediction of overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt treatment: a cohort study.

ABSTRACT:

Background/purpose

Overt hepatic encephalopathy (HE) risk should be preoperatively predicted to identify patients suitable for curative transjugular intrahepatic portosystemic shunt (TIPS) instead of palliative treatments.

Methods

A total of 185 patients who underwent TIPS procedure were randomised (130 in the training dataset and 55 in the validation dataset). Clinical factors and imaging characteristics were assessed. Three different models were established by logistic regression analyses based on clinical factors (Model^C), imaging characteristics (Model^I), and a combination of both (Model^CI). Their discrimination, calibration, and decision curves were compared, to identify the best model. Subgroup analysis was performed for the best model.

SUBMITTER: Yang Y 

PROVIDER: S-EPMC8286937 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature