Glomerular function in relation to fine airborne particulate matter in a representative population sample.

ABSTRACT: From 1990 until 2017, global air-pollution related mortality increased by 40%. Few studies addressed the renal responses to ultrafine particulate [≤ 2.5 µm (PM2.5)], including black carbon (BC), which penetrate into the blood stream. In a Flemish population study, glomerular filtration estimated from serum creatinine (eGFR) and the urinary albumin-to-creatinine ratio were measured in 2005-2009 in 820 participants (women, 50.7%; age, 51.1 years) with follow-up of 523 after 4.7 years (median). Serum creatinine, eGFR, chronic kidney disease (eGFR < 60 mL/min/1.73 m²) and microalbuminuria (> 3.5/> 2.5 mg per mmol creatinine in women/men) were correlated in individual participants via their residential address with PM_2.5 [median 13.1 (range 0.3-2.9) μg/m³] and B

SUBMITTER: Feng YM 

PROVIDER: S-EPMC8290004 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature