Ontology highlight
ABSTRACT:
SUBMITTER: Angala SK
PROVIDER: S-EPMC8294699 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Angala Shiva K SK Li Wei W Boot Claudia M CM Jackson Mary M McNeil Michael R MR
Communications chemistry 20200807 1
Mycobacterial lipoarabinomannan (LAM) in an essential cell envelope lipopolysaccharide anchored both to the plasma and outer membranes. To understand critical biological questions such as the biosynthesis, spatial organization of LAM within the cell envelope, structural remodeling during growth, and display or lack of display of LAM-based antigenicity all requires a basic understanding of the primary structure of the mannan, arabinan and how they are attached to each other. Herein, using enzymat ...[more]