Serum trypsin-like immunoreactivity in dogs with diabetes mellitus.

ABSTRACT:

Background

Concurrent exocrine pancreatic dysfunction and decreased pancreatic organ size are common findings in various stages of human type 1 diabetes mellitus (DM). Exocrine pancreatic insufficiency (EPI) is incompletely described in diabetic dogs.

Objective

To compare canine trypsin-like immunoreactivity (cTLI) of diabetic dogs with that of healthy controls. A secondary aim was to evaluate the correlation between duration of DM and cTLI.

Animals

Thirty client-owned diabetic dogs and thirty client-owned control dogs.

Methods

Cross-sectional study. Diabetic and healthy control dogs were included if they had no clinical evidence of pancreatitis and if serum samples obtained after food was withheld were available. Serum cTLI was measured at a reference laborato

SUBMITTER: Hamilton K 

PROVIDER: S-EPMC8295701 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature