Ontology highlight
ABSTRACT:
SUBMITTER: de Candia P
PROVIDER: S-EPMC8297982 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
iScience 20210722 8
The clinical benefit of convalescent plasma (CP) for patients with coronavirus disease (COVID)-19 is still debated. In this systematic review and meta-analysis, we selected 10 randomized clinical trials (RCTs) and 15 non-randomized studies (total number of patients = 22,591) of CP treatment and evaluated two different scenarios: (1) disease stage of plasma recipients and (2) donated plasma antibody titer, considering all-cause mortality at the latest follow-up. Our results show that, when provid ...[more]