2021 Young Investigator Award Winner: Anatomic Gradients in the Microbiology of Spinal Fusion Surgical Site Infection and Resistance to Surgical Antimicrobial Prophylaxis.

ABSTRACT:

Study design

Retrospective hospital-registry study.

Objective

To characterize the microbial epidemiology of surgical site infection (SSI) in spinal fusion surgery and the burden of resistance to standard surgical antibiotic prophylaxis.

Summary of background data

SSI persists as a leading complication of spinal fusion surgery despite the growth of enhanced recovery programs and improvements in other measures of surgical quality. Improved understandings of SSI microbiology and common mechanisms of failure for current prevention strategies are required to inform the development of novel approaches to prevention relevant to modern surgical practice.

Methods

Spinal fusion cases performed at a single referral center between January 2011 and June 2019 were reviewed a

SUBMITTER: Long DR 

PROVIDER: S-EPMC8299899 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature