Dataset Information

Expert Perspectives on the Performance of Explosive Detection Canines: Operational Requirements.

ABSTRACT: Explosive detection canines (EDC) play an important role in protecting people and property. The utilization of and research on EDCs is often based on personal experience or incomplete knowledge. EDC practitioners (handlers, trainers, and leaders) possess the institutional knowledge necessary to understand EDC operational requirements. This study utilized a qualitative approach with semi-structured interviews of EDC experts (n = 17) from across the employment spectrum. The interviews elicited EDC expert perceptions of the performance of the EDC team and the operational requirements in the physical, climate, operational, and explosive odor environments. Analysis of the data revealed commonalities across all EDCs and utilization-specific differences. To be effective, the EDC team must function well on both ends of the leash, and the handler likely has the greatest impact on the EDC's performance. Common requirements include expectations to perform at a high level in a variety of manmade and natural physical environments and under a range of climate conditions. EDCs must work through the visual, olfactory, and auditory challenges of the operational environment and the countermeasure efforts of those utilizing explosive devices. Utilization-specific differences like patrol or assault training and utilization add additional requirements for some EDCs. The results of this study can be used to inform EDC selection, training, assessment, and deployment, and further research into EDC performance.

SUBMITTER: Farr BD

PROVIDER: S-EPMC8300389 | biostudies-literature |

REPOSITORIES: biostudies-literature

ACCESS DATA

Similar Datasets

Project description:In the Greater Mekong Subregion in Southeast Asia, malaria elimination strategies need to target all Plasmodium falciparum parasites, including those carried asymptomatically. More than 70% of asymptomatic carriers are not detected by current rapid diagnostic tests (RDTs) or microscopy. An HRP2-based ultrasensitive RDT (uRDT) developed to improve the detection of low-density infections was evaluated during prevalence surveys within a malaria elimination program in a low-transmission area of eastern Myanmar. Surveys were conducted to identify high-prevalence villages. Two-milliliter venous blood samples were collected from asymptomatic adult volunteers and transported to the laboratory. Plasmodium parasites were detected by RDT, uRDT, microscopy, ultrasensitive qPCR (uPCR), and multiplex enzyme-linked immunosorbent assay (ELISA). The sensitivity, specificity, and predictive positive and negative values of RDT and uRDT were calculated compared to uPCR and ELISA. Parasite and antigen concentrations detected by each test were defined using uPCR and ELISA, respectively. A total of 1,509 samples, including 208 P. falciparum-positive samples were analyzed with all tests. The sensitivity of the uRDT was twofold higher than that of RDT, 51.4% versus 25.2%, with minor specificity loss, 99.5% versus 99.9%, against the combined reference (uPCR plus ELISA). The geometric mean parasitemia detected by uRDT in P. falciparum monospecific infections was 3,019 parasites per ml (95% confidence interval [95% CI], 1,790 to 5,094; n = 79) compared to 11,352 parasites per ml (95% CI, 5,643 to 22,837; n = 38) by RDT. The sensitivities of uRDT and RDT dropped to 34.6% and 15.1%, respectively, for the matched tests performed in the field. The uRDT performed consistently better than RDT and microscopy at low parasitemias. It shows promising characteristics for the identification of high-prevalence communities and warrants further evaluation in mass screening and treatment interventions.

Dataset Information

Expert Perspectives on the Performance of Explosive Detection Canines: Operational Requirements.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets