Ontology highlight
ABSTRACT:
SUBMITTER: Kirui J
PROVIDER: S-EPMC8303237 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Kirui Jared J Abidine Yara Y Lenman Annasara A Islam Koushikul K Gwon Yong-Dae YD Lasswitz Lisa L Evander Magnus M Bally Marta M Gerold Gisa G
Cells 20210720 7
Chikungunya virus (CHIKV) is a re-emerging, mosquito-transmitted, enveloped positive stranded RNA virus. Chikungunya fever is characterized by acute and chronic debilitating arthritis. Although multiple host factors have been shown to enhance CHIKV infection, the molecular mechanisms of cell entry and entry factors remain poorly understood. The phosphatidylserine-dependent receptors, T-cell immunoglobulin and mucin domain 1 (TIM-1) and Axl receptor tyrosine kinase (Axl), are transmembrane protei ...[more]