Maturation and Protection Effect of Retinal Tissue-Derived Bioink for 3D Cell Printing Technology.

ABSTRACT: Retinal degeneration is a leading cause of incurable vision loss and blindness. The increasing incidence of retinal degeneration has triggered research into the development of in vitro retinal models for drug development and retinal alternatives for transplantation. However, the complex retinal structure and the retinal microenvironment pose serious challenges. Although 3D cell printing technology has been widely used in tissue engineering, including in vitro model development and regeneration medicine, currently available bioinks are insufficient to recapitulate the complex extracellular matrix environment of the retina. Therefore, in this study, we developed a retinal decellularized extracellular matrix (RdECM) from the porcine retina and evaluated its characteristics. The RdECM conserve

SUBMITTER: Kim J 

PROVIDER: S-EPMC8309106 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature