Toxicological Effects of Roundup® on Drosophila melanogaster Reproduction.
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ABSTRACT: Herbicide use has increased dramatically since 2001, particularly Roundup®. Effective in agricultural practice, Roundup® adversely affects non-target organisms, including reproductive and endocrine systems. We exposed fruit flies, Drosophila melanogaster, to either Roundup® Ready to Use, containing pelargonic acid and glyphosate, or Roundup® Super Concentrate, that includes glyphosate and POEA, at sublethal concentrations. Both Roundup® formulations reduced ovary volume with fewer mature oocytes, most adversely at the highest concentration tested. Flies exposed within 2 h of eclosion were affected more than at 4 h, suggesting a critical period of increased ovarian sensitivity. These results support multi-species evidence that glyphosate-based herbicides interfere with normal development of the reproductive systems of non-target organisms.
SUBMITTER: Muller K
PROVIDER: S-EPMC8309847 | biostudies-literature |
REPOSITORIES: biostudies-literature
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