Prognostic nutritional index (PNI), independent of frailty is associated with six-month postoperative mortality.

ABSTRACT:

Introduction

Prognostic Nutritional Index (PNI) is associated with disease and overall survival in patients with cancer. We aimed to assess the relationship between PNI, frailty, and six-month postoperative survival in older patients with cancer.

Methods

In this retrospective study, patients with cancer aged ≥75 who underwent geriatric preoperative evaluation and then proceeded with elective surgery with hospital length of stay of ≥1 day and had six-month follow-up were included. PNI is measured by preoperative [10 × albumin(gr/dl)] + [0.005 × absolute lymphocyte count (per mm³)]. Higher PNI is suggestive of better nutritional status. Frailty was assessed by geriatric assessment. PNI among patients with and without each age-related impairment was evaluated. Pearso

SUBMITTER: Cadwell JB 

PROVIDER: S-EPMC8311543 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature