Evaluation of the safety profile of COVID-19 vaccines: a rapid review.

ABSTRACT:

Background

The rapid process of research and development and lack of follow-up time post-vaccination aroused great public concern about the safety profile of COVID-19 vaccine candidates. To provide comprehensive overview of the safety profile of COVID-19 vaccines by using meta-analysis technique.

Methods

English-language articles and results posted on PubMed, Embase, Web of Science, PMC, official regulatory websites, and post-authorization safety surveillance data were searched through June 12, 2021. Publications disclosing safety data of COVID-19 candidate vaccines in humans were included. A meta-analysis of proportions was performed to estimate the pooled incidence and the pooled rate ratio (RR) of safety outcomes of COVID-19 vaccines using different platforms.

Results<

SUBMITTER: Wu Q 

PROVIDER: S-EPMC8315897 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature