Investigation of the influence of pancreatic surgery on new-onset and persistent diabetes mellitus.

ABSTRACT:

Aim

The management of diabetes mellitus (DM) after pancreatic surgery is a long-standing issue. We aimed to investigate DM concerning pancreatic surgery, including new onset diabetes mellitus (NODM), DM resolution, and the change in insulin excretion before/after pancreatic surgery.

Methods

We retrospectively investigated three different cohorts (total 403 patients) undergoing pancreatectomy. Of those, 275 patients without preoperative DM were investigated for the risk factors of NODM. Fifty-four patients without preoperative DM of the other cohort were assessed for pre/postoperative 24-hour urinary C-peptide excretion (24-hr CPR). To evaluate the influence of pancreatic surgery on DM treatment in patients with preoperative DM, 74 patients were investigated. In all those pat

SUBMITTER: Yamada D 

PROVIDER: S-EPMC8316753 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature