Prevalence of Hashimoto Thyroiditis in Adults With Papillary Thyroid Cancer and Its Association With Cancer Recurrence and Outcomes.

ABSTRACT:

Importance

Hashimoto thyroiditis (HT) has been suggested to be associated with papillary thyroid cancer (PTC) development. However, its association with PTC progression remains unclear.

Objective

To examine the association between HT and PTC presentation and outcomes.

Design, setting, and participants

This retrospective cohort study included a review of patients aged 18 to 75 years who had pathologically confirmed PTC treated at a single center in China from January 1, 2001, to December 31, 2014. Data analysis was performed from November 1 to December 31, 2020.

Exposures

Coexistent HT was defined according to evaluation of postoperative paraffin sections.

Main outcomes and measures

The primary outcome was the association of HT with PTC-related mortality,

SUBMITTER: Xu S 

PROVIDER: S-EPMC8317012 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature