Ontology highlight
ABSTRACT: Patient summary
Addition of prostate volume or prostate-specific antigen density to Memorial Sloan Kettering Cancer Center prediction schemes did not improve the prediction of recurrence of prostate cancer after removal of the prostate.
SUBMITTER: Tzeng M
PROVIDER: S-EPMC8317781 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Tzeng Michael M Vertosick Emily E Basourakos Spyridon P SP Eastham James A JA Ehdaie Behfar B Scardino Peter T PT Vickers Andrew J AJ Hu Jim C JC
European urology open science 20210615
Prostate-specific antigen (PSA) density is an established prognostic marker for prostate cancer. We investigated whether the inclusion of PSA density or prostate volume in the Memorial Sloan Kettering Cancer Center nomograms improves the prediction of biochemical recurrence (BCR) after radical prostatectomy (RP). Among the 11 725 men included, 2140 developed BCR. Neither PSA density nor prostate volume was associated with BCR when added to either the pre-RP or post-RP model (all <i>p</i> values ...[more]