Ontology highlight
ABSTRACT:
SUBMITTER: Qian T
PROVIDER: S-EPMC8319125 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Qian Tongcheng T Heaster Tiffany M TM Houghtaling Angela R AR Sun Kexin K Samimi Kayvan K Skala Melissa C MC
Nature communications 20210728 1
Human pluripotent stem cell (hPSC)-derived cardiomyocytes provide a promising regenerative cell therapy for cardiovascular patients and an important model system to accelerate drug discovery. However, cost-effective and time-efficient platforms must be developed to evaluate the quality of hPSC-derived cardiomyocytes during biomanufacturing. Here, we develop a non-invasive label-free live cell imaging platform to predict the efficiency of hPSC differentiation into cardiomyocytes. Autofluorescence ...[more]