Ontology highlight
ABSTRACT:
SUBMITTER: Zhou ZH
PROVIDER: S-EPMC8321400 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Zhou Zhao-Hua ZH Dharmarajan Sai S Lehtimaki Mari M Kirshner Susan L SL Kozlowski Steven S
PLoS pathogens 20210719 7
Neutralizing antibodies to the SARS CoV-2 spike proteins have been issued Emergency Use Authorizations and are a likely mechanism of vaccines to prevent COVID-19. However, benefit of treatment with monoclonal antibodies has only been observed in clinical trials in outpatients with mild to moderate COVID-19 but not in patients who are hospitalized and/or have advanced disease. To address this observation, we evaluated the timing of anti SARS-CoV-2 antibody production in hospitalized patients with ...[more]