Ontology highlight
ABSTRACT:
SUBMITTER: Yuval O
PROVIDER: S-EPMC8321406 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Yuval Omer O Iosilevskii Yael Y Meledin Anna A Podbilewicz Benjamin B Shemesh Tom T
PLoS computational biology 20210719 7
Complex dendritic trees are a distinctive feature of neurons. Alterations to dendritic morphology are associated with developmental, behavioral and neurodegenerative changes. The highly-arborized PVD neuron of C. elegans serves as a model to study dendritic patterning; however, quantitative, objective and automated analyses of PVD morphology are missing. Here, we present a method for neuronal feature extraction, based on deep-learning and fitting algorithms. The extracted neuronal architecture i ...[more]