Dose Adjustment of Biologic Treatments for Moderate-to-Severe Plaque Psoriasis in the Real World: A Systematic Review.

ABSTRACT:

Introduction

Dose escalation and reduction of biologic treatments are frequent in clinical practice. The aim of this systematic review is to summarise evidence on dose adjustment of biologic treatments for moderate-to-severe plaque psoriasis in the real-world.

Methods

A systematic review of real-world evidence on dose adjustment of biologics for plaque psoriasis was performed. Searches were conducted in BIOSIS Previews^®, Embase^®, International Pharmaceutical Abstracts, MEDLINE^®, and SciSearch^® in March 2020. Real-world studies that reported biologic dose adjustment for moderate-to-severe plaque psoriasis were included.

Results

The search identified 162 papers, and 20 studies with 30,912 patients were included from 2014 to 20

SUBMITTER: Gambardella A 

PROVIDER: S-EPMC8322248 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature