Healthy preconception and early-pregnancy lifestyle and risk of preterm birth: a prospective cohort study.

ABSTRACT:

Background

Preterm birth (PTB) remains a leading cause of neonatal mortality and long-term morbidity. Individual factors have been linked to PTB risk. The impact of a healthy lifestyle, with multiple modifiable prenatal factors, remains unknown.

Objectives

We aimed to examine the associations of preconceptional and early-pregnancy low-risk modifiable factors (individually and in combination) with PTB risk.

Methods

This prospective cohort study included 2449 women with singleton pregnancies in the Pregnancy Environment and Lifestyle Study. PTB was defined as ultrasound-confirmed obstetric estimate-based gestational age at delivery <37 wk. A set of low-risk modifiable factors were identified: healthy weight (prepregnancy BMI: 18.5-24.9 kg/m2) based on clinical measureme

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC8326036 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature