Estimating the effect of nutritional interventions using observational data: the American Heart Association's 2020 Dietary Goals and mortality.

ABSTRACT:

Background

Because randomized trials of sustained dietary changes are sometimes impractical for long-term outcomes, the explicit emulation of a (hypothetical) target trial using observational data may be an important tool for nutritional epidemiology.

Objectives

We describe a methodological approach that aims to emulate a target trial of dietary interventions sustained over many years using data from observational cohort studies.

Methods

We estimated the 20-y risk of all-cause mortality under the sustained implementation of the food-based goals of the American Heart Association (AHA) 2020 using data from 3 prospective observational studies of US men [Health Professionals Follow-up Study (HPFS)] and women [Nurses' Health Study (NHS) and Nurses' Health Study II (NHS II)

SUBMITTER: Chiu YH 

PROVIDER: S-EPMC8326054 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature