Ontology highlight
ABSTRACT:
SUBMITTER: Meyer BP
PROVIDER: S-EPMC8327111 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Meyer Briana P BP Hirschler Lydiane L Lee Seongtaek S Kurpad Shekar N SN Warnking Jan M JM Barbier Emmanuel L EL Budde Matthew D MD
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20210128 8
Despite the potential to guide clinical management of spinal cord injury and disease, noninvasive methods of monitoring perfusion status of the spinal cord clinically remain an unmet need. In this study, we optimized pseudo-continuous arterial spin labeling (pCASL) for the rodent cervical spinal cord and demonstrate its utility in identifying perfusion deficits in an acute contusion injury model. High-resolution perfusion sagittal images with reduced imaging artifacts were obtained with optimize ...[more]