Ontology highlight
ABSTRACT:
SUBMITTER: van der Bijl W
PROVIDER: S-EPMC8327960 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
van der Bijl Wouter W Mank Judith E JE
Evolution letters 20210703 4
The majority of the genome is shared between the sexes, and it is expected that the genetic architecture of most traits is shared as well. This common architecture has been viewed as a major source of constraint on the evolution of sexual dimorphism (SD). SD is nonetheless common in nature, leading to assumptions that it results from differential regulation of shared genetic architecture. Here, we study the effect of thousands of gene knockout mutations on 202 mouse phenotypes to explore how reg ...[more]