A randomized clinical trial of contrast increment protocols for binocular amblyopia treatment.

ABSTRACT:

Background

Most clinical trials of contrast-rebalanced binocular amblyopia treatment used a contrast increment protocol of 10% daily with successful play. Paired with a definition of success requiring only 15-30 min/day of gameplay, this increment protocol could allow children to reach 100% fellow eye contrast in 3-9 hours; however, this may not provide adequate therapeutic time with reduced fellow eye contrast. The purpose of this study was to compare the original protocol against three alternative contrast increment protocols designed to increase the number of treatment hours.

Methods

In this prospective study, 63 amblyopic children (4-10 years; amblyopic eye visual acuity, 20/40-125) were randomly assigned one of four daily contrast increment protocols for 4 weeks, all st

SUBMITTER: Jost RM 

PROVIDER: S-EPMC8328197 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature