Molecular docking of potential inhibitors with the mTOR protein.
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ABSTRACT: The mTOR (mammalian or mechanistic Target of Rapamycin) is linked with oral cancer. Therefore, it is of interest to study the molecular docking-based binding of paclitaxel (a FDA approved drug for oral cancer) and its analogues with mTOR. Hence, we report the binding features of 10-Deacetyltaxol, 7-Epi-10-deacetyltaxol, 7-Epi-Taxol and 6alpha-Hydroxypaclitaxel with mTOR for further consideration.
SUBMITTER: Fathima JS
PROVIDER: S-EPMC8340694 | biostudies-literature |
REPOSITORIES: biostudies-literature
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