Nasal nitric oxide testing for allergic rhinitis patients: Systematic review and meta-analysis.

ABSTRACT:

Background

Nasal nitric oxide (nNO) levels in allergic rhinitis (AR), healthy people or nonallergic rhinitis (NAR) have shown contradicting results in previous studies. By meta-analysis, we reviewed studies that measured nNO in AR patients to assess nNO's ability to discriminate AR from healthy people or NAR.

Methods

We systematically searched PubMed, Cochrane, Embase, Ovid, Web of Science, Wanfang Data, CNKI until December 15, 2020. Differences were expressed as standardized mean differences (SMD) with 95% confidence interval (CI), by random-effects method.

Results

A total of 10 original studies with 561 AR patients, 327 healthy controls, 123 NAR patients were included in the narrative synthesis and 9 studies in the meta-analysis. nNO in AR was significantly increase

SUBMITTER: Wang B 

PROVIDER: S-EPMC8342207 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature