Genetic surveillance for monitoring the impact of drug use on Plasmodium falciparum populations.

ABSTRACT: The use of antimalarial drugs is an effective strategy in the fight against malaria. However, selection of drug resistant parasites is a constant threat to the continued use of this approach. Antimalarial drugs are used not only to treat infections but also as part of population-level strategies to reduce malaria transmission toward elimination. While there is strong evidence that the ongoing use of antimalarial drugs increases the risk of the emergence and spread of drug-resistant parasites, it is less clear how population-level use of drug-based interventions like seasonal malaria chemoprevention (SMC) or mass drug administration (MDA) may contribute to drug resistance or loss of drug efficacy. Critical to sustained use of drug-based strategies for reducing the burden of malaria is the s

SUBMITTER: Ndiaye YD 

PROVIDER: S-EPMC8342550 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature