Dynamic alterations in linear growth and endocrine parameters in children with obesity and height reference values.

ABSTRACT:

Background

Obesity can affect linear growth of children but there is uncertainty regarding the dynamics and potential causes.

Methods

In the population-based LIFE Child and the obesity-enriched Leipzig Obesity Childhood cohorts (8,629 children, 37,493 measurements), recruited from 1999 to 2018 in Germany, we compared height, growth, and endocrine parameters between normal-weight and children with obesity (0-20 years). Derived from the independent German CrescNet registry (12,703 children) we generated height reference values specific for children with obesity (data collected from 1999 to 2020).

Findings

Children with obesity were significantly taller than normal-weight peers, differing at maximum by 7·6 cm (1·4 height, standard deviation scores or SDS) at age 6-8 year

SUBMITTER: Kempf E 

PROVIDER: S-EPMC8343253 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature