Ontology highlight
ABSTRACT:
SUBMITTER: Susini T
PROVIDER: S-EPMC8345064 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Susini Tommaso T Saccardin Giulia G Renda Irene I Giani Milo M Tartarotti Enrico E Nori Jacopo J Vanzi Ermanno E Pasqualini Elisa E Bianchi Simonetta S
Cancers 20210729 15
Among new prognostic factors for breast cancer, the most promising one seems to be FGD3 (<i>Facio-Genital Dysplasia 3</i>) gene, whose expression improves outcome by inhibiting cell migration. The aim of the study was to evaluate the prognostic role of FGD3 in invasive breast cancer in a series of 401 women, treated at our unit, by evaluating the expression of this gene by immunohistochemistry. Patients with high FGD3 expression showed a significantly better disease-free survival (DFS) (<i>p</i> ...[more]