Identification of Rhythmically Expressed LncRNAs in the Zebrafish Pineal Gland and Testis.

ABSTRACT: Noncoding RNAs have been known to contribute to a variety of fundamental life processes, such as development, metabolism, and circadian rhythms. However, much remains unrevealed in the huge noncoding RNA datasets, which require further bioinformatic analysis and experimental investigation-and in particular, the coding potential of lncRNAs and the functions of lncRNA-encoded peptides have not been comprehensively studied to date. Through integrating the time-course experimentation with state-of-the-art computational techniques, we studied tens of thousands of zebrafish lncRNAs from our own experiments and from a published study including time-series transcriptome analyses of the testis and the pineal gland. Rhythmicity analysis of these data revealed approximately 700 rhythmically expressed

SUBMITTER: Mishra SK 

PROVIDER: S-EPMC8346003 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature